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Latest in Cardiology

Integrated Polygenic Risk Scores Offer Implementable Framework For Predicting CV Traits
Integrated polygenic risk scores (PRS) offer an implementable framework for genetic risk reporting and are available as a clinically orderable test, according to a validation study using Mass General Brigham Biobank participants and published April 29 in JACC.
Eagleâ€™s Eye View: Can Cardiorespiratory Fitness Lead to Longer Lifespans?
In this weekâ€™s View, Dr. Eagle looks at endovascular therapy for post-thrombotic syndrome and how it reduces severity and improves quality of life.
Could Site Selection Improve Representation in Coronary Stent PMA Studies?
Premarket approval (PMA) studies for coronary stents were found to not fully reflect the intended-use population (IUP) due to significant underrepresentation of minority participants and modest underrepresentation of women, according to research on the enrollment implications of site selection published April 29 in JACC.
Heart Failure Trials Featured at ACC.26
ACC.26 featured several late-breaking heart failure clinical trials, including two focused on subgroups of heart failure that until now had limited data to guide therapies.
NOBLE: Is PCI Equally as Safe as CABG For Patients With Unprotected Left Main CAD?
No significant difference was observed in all-cause mortality at 10 years between PCI and CABG in patients with unprotected left main coronary artery disease (CAD) and no additional complex lesions, according to the final results of the NOBLE study published April 4 in The Lancet.
Keeping it Simple: Top 10 Things to Know About the 2026 Dyslipidemia Guideline
In this interview, Kim Allan Williams, Sr., MD, MACC and Roger S. Blumenthal, MD, FACC discuss key takeaways from the 2026 Dyslipidemia Guideline.
Implications of ACC.26 Prevention Trials For Future Guidelines
The VESALIUS-CV trial primary prevention analysis was a prespecified evaluation of use of evolocumab in 3,655 trial participants who had elevated LDL cholesterol (LDL-C) values but no evidence of significant atherosclerotic cardiovascular disease (ASCVD), defined as no prior revascularization, no arterial stenosis...
Is Same-Day Discharge Safe After M-TEER?
Same-day discharge (SDD) following mitral transcatheter edge-to-edge repair (M-TEER) was found to be uncommon, but compared with next-day discharge (NDD) it was associated with a similar risk of 90-day readmission and lower costs for the index hospitalization, according to research presented April 25...
TRIDENT: Antihypertensive Triple Pill Lowers Stroke Risk, Improves BP After Intracerebral Hemorrhage
Treatment with a combination of three low-dose antihypertensive agents in a single pill in addition to standard care was associated with a lower incidence of recurrent stroke and major cardiovascular events, and improvements in blood pressure (BP), compared with placebo, among patients with a history...
ACC CardiaCast: New Guidelines for Managing Dyslipidemia: What You Can Do Now
In this episode, Drs. Christie Ballantyne and Eugenia Gianos discuss updates regarding the management of dyslipidemia released in new guidelines from the ACC and AHA Joint Committee on Clinical Practical Guidelines.