Clinic News Latest in CardiologyViet Le, DMSc, MPAS, PA-C, FACC, Named CardioSmart EditorThe ACC has named Viet Le, DMSc, MPAS, PA-C, FACC, to lead its CardioSmart patient engagement program.Smart Science, Real Solutions: ACC Asia 2025 Tackles Heart Health Challenges Across AsiaThe ACC and Singapore Cardiac Society (SCS) are in Singapore for the ACC Asia 2025 Together With SCS 36th Annual Scientific Meeting, bringing together leading experts and cardiovascular clinicians from across Asia to examine emerging trends and evidence-based strategies in the prevention and management of patients with heart disease.ACC Cardio-Obstetrics Member Section Advocates For Legislative Solutions to Improve Maternal HealthMembers of ACC's Reproductive Health & Cardio-Obstetrics Member Section met virtually with representatives from 11 congressional offices on May 7 to push for stronger federal action on maternal health.Rapid Initiation, Titration of GRMT Feasible in Patients With HFrEFInitiating guideline-recommended medical therapy (GRMT) in patients with heart failure with reduced ejection fraction (HFrEF) quickly after diagnosis is feasible in a real-world setting, according to findings from the ongoing TITRATE-HF registry ...OCT-Guided PCI Performs Better Than Angiographic PCI GuidanceThe use of optical coherence tomography (OCT) plus predefined algorithmic management achieved better stent implantation results than angiographic guidance when performing PCI in patients with calcified lesions...Is Aficamten Plus Disopyramide More Effective Than Aficamten Alone in oHCM?The addition of aficamten to disopyramide was effective and well-tolerated in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) with persistent left ventricular overflow tract (LVOT) obstruction, and the withdrawal of disopyramide did not reduce the effectiveness of aficamten...Significant Physician-Level Variation Persists in Contrast Volume During PCIThere was a consistent yet modest decline in contrast volume used during PCI between 2018 and 2022, with notably less contrast in patients at high risk of acute kidney injury (AKI) and significant variation at the physician level...Proportion of Patients Achieving BP Control Plateaus Despite Increasing Medication PrescriptionsA sizable proportion of outpatient cardiovascular patients in the U.S. have not achieved guideline-directed blood pressure (BP) goals, even though prescriptions for antihypertensive medications have increased over time, according to recent study ...Contribution of Adiposity vs. Insulin Resistance in Patients With HFpEFAmong patients with heart failure with preserved ejection fraction (HFpEF), cardiac remodeling, hemodynamics and functional impairment were independently correlated with adiposity while insulin resistance (IR) was not, according to results from the PVDOMICS study...ORBITA-2: DSE Predicts PCI Efficacy in Patients With CADIschemia as detected by dobutamine stress echocardiography (DSE) predicted the placebo-controlled efficacy of PCI in patients with single- and multivessel stable coronary artery disease (CAD) taking little or no antianginal medication, according to a secondary analysis of the ORBITA-2 trial...