Clinic News Latest in CardiologyInnovation in Defibrillator Technology: The Novel OmniaSecureâ„¢ LeadTransvenous leads are the weak link in any implantable transvenous pacemaker or defibrillator system. Transvenous leads are associated with vascular occlusions, tricuspid regurgitation, endocarditis, and lead failure.One Big Beautiful Bill Act Implementation: What You Need to KnowThe One Big Beautiful Bill Act (OBBBA) became law on July 4, cutting more than $1 trillion in Medicaid funding and making substantial changes to the federal student loan program.ACC Chapters Increasing AED Access Across the USIncreasing access to AEDs has been a priority issue for several ACC State Chapters, guiding their advocacy efforts throughout the 2025 state legislative sessions. In the past year, more than 20 states have introduced related legislation, with ACC Chapters playing a major role in advocating for successful passage...Does Number of CVD Risk Factors Influence Plaque Vulnerability in ACS?The number of cardiovascular risk factors was strongly associated with greater plaque vulnerability, especially for culprit lesions, in patients with acute coronary syndromes (ACS), according to new research published in JACC.Better Cardiac Outcomes With Missense LMNA Variants Than Truncating VariantsTruncating LMNA variants are associated with worse arrhythmic outcomes regardless of variant location, whereas missense variants affecting the tail domain and located in exons 7-12 have better arrhythmic and heart failure (HF) outcomes...SURMOUNT-5: Greater Loss of Weight, Waist Circumference With Tirzepatide Than SemaglutideTirzepatide leads to significantly greater loss of weight and weight circumference compared with semaglutide among adults with obesity but without diabetes, according to new results from the SURMOUNT-5 phase 3b trial, published in The New England Journal of Medicine.Higher Survival Benefit After 2018 U.S. Heart Transplantation Allocation Policy ChangeThe 2018 U.S. heart allocation policy change has resulted in an increased survival benefit of heart transplantation due to improved stratification and prioritization of transplant candidates, according to a study published July 7 in JACC: Heart Failure.Deep Learning in Automating Cardiac Imaging: Challenges and Mitigation StrategiesWhen applying imaging analysis based on deep learning (DL) models, training data and generalization were found to challenge the performance of DL algorithms for automated cardiac measurements, while evaluation metrics were found to challenge the ability to detect underperforming algorithms...Is Disease Progression Similar in ARVC and Exercise-Induced Arrhythmogenic Cardiomyopathy?While the cardiac structural and functional phenotypes were similar at baseline in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) with desmosomal variants and those with genotype-negative exercise-induced arrhythmogenic cardiomyopathy (EiAC)...Predictors of High-Grade Atrioventricular Block After TTVR | TRIPLACE RegistryBaseline left bundle branch block or left anterior or posterior fascicular block in patients undergoing transcatheter tricuspid valve replacement (TTVR) are associated with a higher risk of high-grade atrioventricular block (HAVB) post procedure...